Organizational structure

Project structure

Lead investigators are:

The aim of this proposal is the integration of 50 European leukemia laboratories to

establish molecular monitoring of residual disease according to standardized methods,
optimize early detection of kinase mutations, including new very sensitive techniques,
translate the obtained data into clinical application.

At least one laboratory per country or region should participate to serve as a national reference laboratory. Most of the participants have a longstanding cooperation across Europe and cooperate within the European LeukemiaNet. These participants are complemented by the integration of partner groups located in Australia and in US.
A prerequisite of European harmonization of molecular monitoring is that, beyond reaching a critical mass, virtually all leukemia study groups are apt for full implementation. The European LeukemiaNet provides a unique opportunity to distribute and test standards in the different branches of leukemia diagnostics including molecular monitoring and analysis of mechanisms of treatment resistance. This investment is highly cost-effective, reshapes the European infrastructure and achieves long lasting sustainability and added value.

Laboratories in the standardization process to Complete Molecular Response

Phase 1:

Phase 2:

Created by: Hellenbrecht , generated 2007/12/19 , last changed: 2011/07/14